Tya kashi na biyu
Dangantaka tsakanin NAD+ da cuta:
Raunin da ya haifar da rashin daidaituwa na NAD + metabolism
01.NAD+ da kamuwa da cuta
A halin yanzu an san cewa kamuwa da ƙwayoyin cuta da yawa zai haifar da raguwa sosai a ciki n gyara lalacewa ta hanyar kunna PARPs, ta yadda za a share ƙwayoyin cuta da yaƙar kamuwa da cuta.
02.NAD+ da tsufa
Bincike ya nuna cewa matakan NAD+ na jiki suna raguwa da shekaru. Rage matakan NAD+ ɗaya ne daga cikin manyan abubuwan da ke haifar da lalacewar ilimin halitta kuma zai haɓaka tsufa. Gwaje-gwaje sun tabbatar da cewa ƙarin NAD + na iya jinkirta tsufa.
03. Ragewar NAD + yana haifar da rashin aiki na mitochondrial
Rashin aikin mitochondrial ɗaya ne daga cikin alamomin tsufa, kuma ƙarancin NAD + shine muhimmin dalilin wannan yanayin. Mayar da matakan NAD + ta hanyar NAD + kari da sauran hanyoyin na iya inganta aikin mitochondrial sosai.
04.NAD+ da damuwa na oxidative
Tsayawa daidaitaccen rabo na NADH/NADPH na yau da kullun na iya rage yawan damuwa ta hanyar salula, kuma NAD + shine ainihin mai sarrafa wannan rabo.
;05.NAD+ da circadian rhythm
Haɓaka NAD+ da haɓaka abun ciki na NAD+ na jiki sune abubuwan da suka wajaba don sel don kiyaye hawan circadian.
;06.NAD+ da cututtuka na rayuwa
Ga mutanen da ke da nau'in ciwon sukari na 2, kiba da cututtukan hanta maras giya, matakan NAD + a cikin ƙwayoyin nama zasu ragu sosai. Kariyar NAD + na iya haɓaka matakan NAD +, ta haka inganta yanayin waɗannan cututtukan guda uku na rayuwa.
07.NAD+ da gazawar koda
A cikin berayen gwaji tare da gazawar koda, an gano cewa NAD + ya ragu sosai, kuma ƙarfin haɗin NAD + a cikin kodan shima ya ragu, wanda ya haifar da raguwar matakan NAD+.;Bugu da ƙari, NAD + kuma yana taka muhimmiyar rawa a cikin nau'o'in cututtukan neurodegenerative na yau da kullum da cututtukan zuciya.
kashi na uku
Taimaka cika NAD+ tare da NMN
; NAD + shine coenzyme don ɗaruruwan mahimman enzymes na rayuwa a cikin sel, kuma yana shiga cikin mahimman hanyoyin salula da yawa azaman ƙwayar sigina, mai alaƙa da haɓakar kuzarin kuzari, glycolysis, kwafin DNA da sauran ayyukan. Kuma da yawa daga cikin abubuwan da ke sama ba su rabu da sa hannun NAD +, don haka ƙara NAD + yana da matukar mahimmanci.
NAD+ precursor: NMN
Zamu iya haɓaka matakan NAD+ na ɗan adam ta hanyar ɗaukar NMN baki ɗaya. NMN shine mafarin haɗin NAD + (coenzyme I) a cikin jikin mutum. Yawancin gwaje-gwajen dabba sun tabbatar da cewa NMN na iya haɓaka matakin NAD + da sauri a cikin sel kuma yana da aminci sosai.
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Lokacin aikawa: Dec-26-2023
