Babban aiki game da Spermidine da Spermidine trihydrochloridecan a cikin bincike

Babban aiki game daSpermidine kumaSpermidine trihydrochlorideiya a bincike

Spermidine [N- (3-aminopropyl) -1,4-diaminobutane] cikakken triamine na layi ne wanda aka fi sani da shi azaman tsaka-tsaki a cikin haɗin maniyyi. Yana da dabarar kwayoyin halitta C1H19N3 da kuma molar taro 145.25 g/mol kuma karami ne, mai narkewa da ruwa, kwayoyin amphiphilic tare da ikon shiga cikin membranes na halitta. Yana faruwa a ko'ina cikin halittu da yawa, ba tare da la'akari da rarrabuwa taxonomic ba.

Spermidine na iya haɗa nau'ikan kwayoyin halitta daban-daban, yana sa su da amfani sosai. Suna tallafawa matakai ciki har da haɓakar tantanin halitta, kwanciyar hankali na DNA, yaduwar kwayar halitta da apoptosis. Ya bayyana cewa polyamines suna aiki a irin wannan hanya zuwa abubuwan haɓaka yayin rarraba tantanin halitta. Wannan shine dalilin da ya sa spermidine yana da mahimmanci ga ci gaban nama mai lafiya da aiki.

1.Anti-mai kumburi Properties na Spermidine ga ciwon daji da kuma zuciya da jijiyoyin jini Properties

A cikin binciken 2016, an gano spermidine don juyawa agogon tsufa da inganta aikin zuciya da jijiyoyin jini a cikin tsofaffin beraye. A matakin gabobin jiki, tsarin zuciya da aiki ya inganta a cikin tsofaffin berayen da aka ba da spermidine. Hakanan an inganta narkewa a cikin waɗannan berayen saboda maido da tsarin mitochondrial da aiki bayan kari na spermidine.

2. Spermidineaiki a matsayin anti-tsufa sinadaran

Dangane da tsawon rai, yawancin binciken dabbobi sun nuna cewa shan spermidine yana ƙara tsawon rayuwa kuma yana hana hanta fibrosis da ciwon hanta. Hakanan yana da alama gaskiya game da abinci mai wadatar polyamine. Har ila yau, akwai wasu shaidun da ke nuna cewa yana ƙara juriya ga damuwa, kuma raguwar shekarun haihuwa a cikin spermidine yana tallafawa ci gaban cututtukan da suka shafi shekaru.

3.Spermidine trihydrochlorideiya rilmantar da Fahimtar Ragewa

Bincike da aka buga a cikin mujallar Cell Reports a cikin 2021 cikakkun bayanai cewa maniyyi na abinci yana inganta fahimta da aikin mitochondrial a cikin kwari da mice, kuma yana ba da wasu bayanan ɗan adam mai yiwuwa.