A cikin 1998, masanin Jafananci Akiu et al. cirewa da ware arbutin daga ganyen bearberry kuma ya sami wani abu wanda zai iya cimma tasirin fata. Yana yana da daban-daban pharmacological effects kamar anti-mai kumburi, antibacterial, antitussive, expectorant, kuma antiasthmatic. , Hakanan mai hana tyrosinase ne a cikin melanocytes na ɗan adam, don haka da sauri ya zama masoyin masana'antar fata.
Arbutin, kuma aka sani daarbutin , shine p-hydroxyphenyl-D-glucopyranoside na sinadarai kuma yana cikin nau'in farin allura-kamar lu'ulu'u ko foda. Sauƙi mai narkewa a cikin ruwan zafi, methanol, ethanol da mafita mai ruwa na propylene glycol da glycerol, amma maras narkewa a cikin ether, chloroform, ether petroleum da sauran kaushi. Tsarin kwayoyin halitta shine C12H16O7, kuma tsarinsa shine kamar haka:
Arbutin kwayar halitta ce da ta ƙunshi ƙungiyoyin halitta waɗanda suka ƙunshi ƙungiyoyin polyvalent hydroxyl. Maganin ruwa mai ruwa ba shi da launi kuma mai haske, don haka yana da dacewa mai kyau kuma ana iya amfani dashi cikin sauƙi azaman ƙari a cikin creams. Bugu da ƙari, yana da kyawawan kaddarorin m, ya fi dacewa don amfani da kayan shafa, yana da laushi mai laushi da jin dadi, kuma yana da ɗan fari da tsabta bayan aikace-aikacen. Wadannan halaye an ƙaddara su ta hanyar tsarin polyhydroxyl glycosides.
Bugu da ƙari, arbutin yana da tasirin hanawa na musamman akan melanin.
Melanin abu ne mai launin duhu mai duhu wanda zai iya haifar da launin fata. An kafa shi ta hanyar iskar oxygen ta tyrosine ta hanyar tyrosinase. Za mu iya ɗaukar tyrosinase a matsayin babban adadin enzyme mai iyakancewa don samar da melanin a cikin fata. Ayyukan tyrosine yana ƙayyade adadin melanin da aka kafa.
Yadda za a hana aikin catalytic na tyrosinase yana ɗaya daga cikin mahimman kwatancen bincike a cikin masana'antar fata. Ma'aikatan fararen fata na gargajiya irin su hydroquinone (1,4-hydroquinone) na iya hana aikin tyrosinase yadda ya kamata kuma suna da wani tasiri na depigmentation akan fata. Duk da haka, amfani da waje na iya haifar da halayen ban haushi kuma yana iya haifar da iƙirarin fata cikin sauƙi, tsauri, da bawo. Alamun rashin lafiyar kamar dandruff da erythema na iya haifar da lalacewa ta dindindin, don haka aikace-aikacen sa na asibiti yana ƙarƙashin wasu iyakoki.
Tsarin arbutin yayi kama da na hydroquinone. Tsarinsa yana da ƙwayoyin glucose guda ɗaya fiye da hydroquinone, yana sa ya fi kwanciyar hankali kuma ya fi dacewa da fata. Hakanan zai iya hana aikin tyrosinase da kyau da samar da melanin. , bat kawai zai iya cire stains, amma kuma yana da wasu kwayoyin cuta da kuma maganin kumburi.
Yana da ƙananan cytotoxicity kuma yana da lafiya kuma ba mai guba ga fata ba. Zai iya hana aikin tyrosinase yadda ya kamata kuma ya hana samuwar melanocytes. Hakanan yana iya haɗa kai tsaye tare da tyrosinase don haɓaka bazuwar melanin. da kuma fitar da ruwa don rage adadin melanin a cikin fata, don haka arbutin shine mafi kyawun fili da mutane ke nema.
Dangane da tsari daban-daban, ana iya raba arbutin zuwa α-arbutin, β-arbutin da deoxyarbutin (D-arbutin).
Tun da α-arbutin yafi samuwa ta hanyar juyin halitta da haɓakar enzymatic, kuma ma'auni na samarwa yana iyakance, yawancin arbutin a halin yanzu akan kasuwa shine β-arbutin, amma tasirin fata yana da kyau kamar α-arbutin. Daya cikin goma sha biyar.
Bincike ya nuna cewa yana da kyau a ƙara 3% arbutin a cikin kayan kwalliya, wanda kashi 90% yana da tasiri wajen lalata freckles, spots malam buɗe ido da ajiyar melanin.
Dukansu α-arbutin da β-arbutin suna da ruwa mai narkewa, kuma tsarin lecithin na lecithin mai nau'i biyu na membrane na sel epidermal na ɗan adam ya fi dacewa don ɗaukar abubuwan da ke narkewa mai narkewa, don haka deoxyarbutin ya kasance.
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Lokacin aikawa: Afrilu-12-2024
